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Gummies tested in this research were plant-based gummies, so the carbohydrates% was around 70–100%. There were no significant differences in age, BMI, and fasting blood glucose between both genders at baseline (Table 4). The average age and BMI of males was 28.6 ± 4.3 years old and 21.3 ± 1.3 kg/m2, while the average age and BMI of females was 27.4 ± 3.1 years old and 22.2 ± 1.4 kg/m2, respectively. This prospective crossover study enrolled healthy adults and was conducted from July 2020 to September 2020. Experimental results showed that, compared with high-GI food, low-GI gummies exhibited significantly improved postprandial glycemia, regardless of available carbohydrate levels. Our study indicated that the P-SG and T-SG groups elicited better glucose tolerance. In this research, the available carbohydrates of all samples in all experiments were kept the same, indicating the absorbable glucose should be identical if no other influential factors were involved. Hence, in order to confirm the main cause of the difference in metabolism capacity between males and females, carbohydrates need to be assigned according to lean body mass in future studies. Lean body mass in males is usually heavier than in females, and the skeletal muscle is the most important organ of energy metabolism. As a result, the gummy dosage form with its chewable characteristics is more likely to become a candy dosage form suitable for people with glucose metabolism disorders. Consistent with hypothesis, the in vitro digestion result showed that, in the oral phase, glucose release rate was slower in gummy form than in powder form. The study performed by Sato et al. also proved that an increase of chewing time led to a reduction in blood glucose levels after breakfast and boosted insulin secretion . Marketers rely on ads with people who recommend the product. Companies offer many types of nonsurgical penis-enlargement treatments. 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