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Topical EMLA cream is also recommended, but the reduction of penile sensation may limit the acceptability of this treatment option. Topical EMLA cream is also recommended, but the reduction of penile sensation may limit the acceptability of this treatment option.The British Association for Sexual Health and HIV Special Interest Group for Sexual Dysfunction14 also recommends SSRIs and clomipramine as they have the strongest evidence for their efficacy. Paroxetine (783% IELT increase, 95% CI, 499–1228), clomipramine (360% IELT increase, 95% CI, 200–435), sertraline (313%, 95% CI, 161–608), and fluoxetine (295%, 95% CI, 200–435) exerted a significant delay in the IELT compared with placebo.6 In addition to having natural ingredients, the top 5 testosterone boosters also offer the most value for your money, allowing you to spend once on a supply that will last you months. 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