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Short sleep duration caused by sleep disorders or lifestyle might provoke the over-activity of the HPA axis, the imbalance of ANS, aberrant SREs and low levels of testosterone. Erectile dysfunction (ED) is defined as the inability to acquire or maintain penile erection for satisfactory sexual performance.12 Although ED is not a fatal condition, it bothers a large proportion of males around the world.13,14 It is suggested that more than 80% of patients with ED have organic etiologies, including vascular, neurological and endocrine factors.12 However, ED still involves the psychological component, especially in younger males.15 Thus, it must be pointed out that previous psychological problems and the disturbance of psychosocial process, such as sleep homeostasis, may be involved in the pathophysiology of ED. PT-141, while not a testosterone booster, enhances libido and sexual performance by switching on arousal signals in the brain (in both men and women). 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The four states with lowest female literacy are Bihar (51.5%), Rajasthan (52.1%), Jharkhand (55.4%) and Jammu and Kashmir (56.4%).