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Clinical trials discussed in this review were selected based on a duration of testosterone replacement therapy of no less than 6 months, with several follow-up time points, and which reported statistically significant increases in testosterone levels upon the initiation of treatment and throughout the timeframe of the clinical trial. As with most other drugs, the frequency and severity of hepatic adverse effects from AAS arise from several factors including formulation of the drug, route of administration, dosage, duration, and idiosyncratic responses.79 Hepatotoxic effects of testosterone occur due to slower clearance of anabolic steroids like testosterone. My starting weight was 185lbs. I have been watched by my doctor and this drug has been helping me . She currently has extreme blood pressure issues now and is on new medication. I've been on this for two and a half months. But testosterone boosters often contain fewer components that target erection strength and semen quality. 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