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Altogether, the available clinical studies and experience to date suggest that KMT is feasible in patients with CKD and does not harm the kidneys but rather has beneficial effects including CKD remission. Upcoming controlled clinical trials will evaluate long-term outcomes on metabolic and renal health. Similarly, overweight status and obesity were shown to predict faster CKD progression in individuals with ADPKD . Beneficial effects of KMT on CKD may be independent of the etiology of CKD and act on the progression of the disease rather than only the trigger. Altogether, SGLT2 inhibition could be considered a ‘light’ version of KMT that, unfortunately, is accompanied by drug-induced adverse effects . Arguably, the same effect could be achieved by ingesting 80 g less sugar/starch per day, which is the equivalent to about two cans of soda. It should be noted that sodium–glucose cotransporter 2 (SGLT2) inhibitors, which are now widely prescribed to CKD patients and often hailed as a breakthrough treatment, work on the same principle as KMT, albeit less effectively . In addition to serving as an energy source, BHB is also a signaling molecule that impacts multiple cellular pathways including its strong inhibition of the NLRP3 inflammasome leading to its potent anti-inflammatory properties. In the presence of insulin, excess carbohydrates are converted to triglycerides and stored in adipose tissues leading to obesity. If hyperglycemia triggers CKD, it is a logical conclusion that hyperglycemia should be ameliorated as much as possible to prevent further renal health deterioration. Whereas the exact mechanisms may still be opaque, chronic hyperglycemia has direct effects on the kidneys, eventually causing vascular and tubular damage, chronic inflammation and fibrosis (Fig. 1). In this review, we will not focus on discussing whether animal or plant foods are preferable for CKD, although there is emerging data on PLADO and PLAFOND diets [7, 8]. This is perhaps because investigators themselves consume different types of foods and may wish to prove that their own dietary preferences are the optimal diet for the medical conditions of others, as seen in notorious opinion fights between vegans and carnivores. The only requirement is that carbohydrate intake is restricted sufficiently and that triglyceride intake is correspondingly increased. For example, irradiation destroys a significant percentage of whatever vitamin B1 a food may contain. County X and County Y have similar terrain, but the population density of County X is significantly higher than that of County Y. Therefore, a wind farm proposed for one of the two counties should be built in County Y rather than in County X.Which of the following, if true, most seriously weakens the planner's argument? 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