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The authors concluded that given the unmet clinical needs, testosterone appears to be a promising therapy to improve functional capacity in patients with HF. The Society for Endocrinology state that testosterone treatment in patients with a well-founded diagnosis of classical hypogonadism is effective and safe. An elevated luteinizing hormone level with a normal testosterone level is more frequent (5-6%), but this does not necessarily imply an inexorable progression towards frank primary gonadal insufficiency, as LH can spontaneously revert to normal particularly among younger men, possibly because the earlier blood sampling having coincided with an LH pulse. However, there is not enough evidence to clearly state that the benefits of testosterone-replacement therapy outweighs the risks of testosterone-replacement therapy in aging males. 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