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Virtual ethnography consisted of ‘digitally tracing’ interactions among people who use drugs on online forums such as Bluelight and Reddit, and locating descriptions of sex-on-drug experiences via these mediums and in the ‘psychoactive vaults’ on the website Erowid. While we do not eclipse questions of agency and resistance, our findings suggest that enhancing sex through drug consumption represents one of a multiplicity of possible consumer choices made by ‘sensation gatherers’ (Bauman, 2003) in the sexual marketplace of the twenty-first century. We argue that this process of inhabitation necessarily informs individual drug users’ motivations for using substances for enhancement, also providing a basis upon which illicit drugs are seen to reappropriate or imitate the effect of legal pharmaceuticals. 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