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In the Chinese medical teaching, kidneys control sexual function; hence foods and herbs such as this can invigorate impotency and infertility increasing semen production as well (5). The purpose of this study was to evaluate the effect of nutraceutical supplementation with β‐carotene, lutein, lycopene, casein, selenium, docosahexaenoic acid (DHA, omega‐3), l‐carnitine, vitamin A, vitamin C and vitamin E on semen quality in Quarter Horse stallions. Therefore, this study hypothesized that supplementation with various antioxidants of nutraceutical origin would improve semen quality in Quarter Horse stallions. This study aimed to evaluate the effect of nutraceutical supplementation on semen quality in Quarter Horse stallions. Based on the results, it is concluded that nutraceutical supplementation improved semen parameters in Quarter Horse stallions. Semen from six Quarter Horse stallions was assessed for 4 months every 20 days using the computer‐assisted semen analysis system. This study was approved by the Ethics Committee of the Second Affiliated Hospital, Zhejiang Chinese Medical University, with the identifier 2019-KL (S1 proof of ethics approval). This study conformed to the ethics principles set forth by the Declaration of Helsinki. Foundation provides research funds and evaluates the research results, but is not involved study design, data collection, analysis, the decision to publish or preparation of the manuscript. We would like to thank Professor Ferguson D for creating the Sexual Encounter Profile (SEP) questionnaire, which has been pivotal for sexual dysfunction research. We would like to thank Dr Chunbao Mo (School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China) for providing professional statistical advice during the design of this study and for providing support in the subsequent data analysis. 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