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On the downside, like many supplements, individual results may differ, and noticeable changes might take time and consistency. Animal studies and pilot clinical trials support the potential of Boswellia serrate gum resin extract in the treatment of a variety of inflammatory diseases including osteoarthritis [19,20,36], and a study of 75 patients with osteoarthritis showed that Boswella serrate extract safely reduced pain and improved physical functioning . Ginger has gained considerable attention in developed countries in recent years, especially for its use in the treatment of inflammatory conditions, and a study of patients with osteoarthritis showed a moderate effect of ginger extract in reducing symptomatology .