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Few clinical reports and few data were found for the side effects of bitter orange (C. aurantium), muirapuama (P. olacoides), and kanna (S. tortuosum), and only preclinical reports were found for muirapuama. However, they did not come as a complete surprise, because these plants have been used for centuries or millennia in traditional medicines and modern medicine has considerably benefited from these ingredients and preparations . These mild effects were not anticipated, considering the mechanism of action of these plants. Kratom (M. speciosa) and yohimbe presented the highest rate of side effects, but yohimbe’s general toxicity is mainly cardiovascular, due to its effects on the NO pathway. As expected, all the plants involved are libido-enhancing aphrodisiacs altering neurotransmission, although ginseng (P. ginseng and P. quinquefolius) and yohimbe (P. johimbe), and kanna (S. tortuosum) also enhance sexual potency. Are eggs good for testosterone? 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