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Similar to the short-chain fatty acids and unlike long-chain triglycerides (LCTs), MCTs do not require the actions of bile, nor micellar-chylomicron mediated absorption into the lymphatics and instead are diffused directly into the hepatic portal vein and preferentially converted into bio-available ketone bodies in the liver. Both 2 g and 4 g of butyric acid were demonstrated to be more ketogenic than either 5 g of leucine, or 5 or 10 g of O-MAG (St-Pierre et al., 2017). Urinary excretion of acetone (a ketone body) is increased in phloridzinised dogs and fasting rats after feeding with acetic acid (MacKay et al., 1940). 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