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So it’s difficult to know what to expect from taking these medications. Compounded semaglutide comes in a variety of dosage forms beyond injections. In this blog post, we’ll take a look at the evidence to see if this medication is effective for people trying to lose weight. If you’re obese or overweight and have diabetes, you may be wondering if Semaglutide (Wegovy or Ozempic) can really help with weight loss. With close monitoring by a health care provider, paying attention to any problems and periodically reassessing whether patients still need to be on the drug, “we can do this safely,” Low Wang says. 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