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But warned the time change sometimes triggers chronic sleep issues that persist for months. Because our circadian rhythm is synced with the sun, having less light in the morning and more in the evening makes it harder to be alert during the day and sleep at night. This clock orchestra not only determines when we sleep but also regulates our metabolism, body temperature, our emotions, aspects of cognition and several hormones. In sum, ingestion and smoking of Δ9-THC seem to produce similar subjective effects, and CBD may attenuate these effects, at least in experienced cannabis users. Few laboratory studies have been undertaken using actual cannabis-infused edibles. By contrast, several double-blind studies report comparable subjective effects for dronabinol and smoked cannabis when dose and time after administration are taken into account (Haney et al., 2007; Haney, Rabkin, Gunderson, & Foltin, 2005; Issa et al., 2014). 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