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Melatonin acutely improves the neuroendocrine architecture of sleep in blind individuals. Sandyk, R. Melatonin and maturation of REM sleep. Ray, C. A. Melatonin attenuates the sympathetic nerve responses to orthostatic stress in humans. Koc, M., Taysi, S., Emin, Buyukokuroglu M., and Bakan, N. The effect of melatonin against oxidative damage during total-body irradiation in rats. [Effect of melatonin on lymphocyte proliferation and production of interleukin-2 (IL-2) and interleukin-1 beta (IL-1 beta) in mice splenocytes].